Thawani Lab
Publications
Thawani A#, Nogales E, Collins K. Structural and biochemical studies of mobile retrotransposon proteins in action. Current Opinion in Structural Biology (2025). PMID: 40334519 [pdf] (# corresponding author)
Thawani A*#, Rodriguez-Vargas A*, Van Treeck V, Hassan NT, Adelson DL, Nogales E#, Collins K#. Structures of vertebrate R2 retrotransposon complexes during target-primed reverse transcription and after second strand nicking. Science Advances (2025). PMID: 40540573 [pdf]
Thawani A#, Florez-Ariza AJ, Nogales E#, Collins K#. Template and target site recognition by human LINE-1 in retrotransposition. Nature (2024). PMID: 38096901 [pdf]
(# corresponding authors)
Covered in Nature News and Views and Trends in Cancer
Perez-Beroldi JM, Zhao Y, Thawani A, Yildiz A, Nogales E. HURP regulates Kif18A recruitment and activity to synergistically control microtubule dynamics. Nature Communications (2024).[pdf]
Commentary
Akanksha's PhD and prior work
Cammarata G, Erdogan B, ... Thawani A, ... Lowery LA. The TOG5 domain of CKAP5 is required to interact with F-actin and promote microtubule advancement in neurons. Molecular Biology of the Cell (2024). PMID: 39504455 [pdf]
Thawani A, Petry S. Molecular insight into how the gamma-Tubulin Ring Complex makes microtubules. Journal of Cell Science (2021). PMID: 34297125 [pdf]
Thawani A, Rale MJ, Coudray N, Bhabha G, Shaevitz JW, Stone HA, Petry S. The transition state and regulation of gamma-TuRC mediated microtubule nucleation revealed by single molecule microscopy. eLife (2020). PMID: 32538784 [pdf]
Alfaro-Aco R, Thawani A, Petry S. Biochemical reconstitution of branching microtubule nucleation. eLife (2020). PMID: 31933480 [pdf]
Thawani A, Stone HA, Shaevitz JW, Petry S. Spatiotemporal organization of branched microtubule networks. eLife (2019). PMID: 31066674 [pdf]
Thawani A*, Kadzik RS*, Petry S. XMAP215 is a microtubule nucleation factor that functions synergistically with the gamma-tubulin ring complex. Nature Cell Biology (2018). PMID: 29695792 [pdf] (* co-first authors)
Song JG, King MR, Zhang R, Kadzik RS, Thawani A, Petry S. Mechanism of how Augmin directly targets the gamma-tubulin ring complex to microtubules. Journal of Cell Biology (2018). PMID: 29875259 [pdf]
Alfaro-Aco R, Thawani A, Petry S. Structural analysis of the role of TPX2 in branching microtubule nucleation. Journal of Cell Biology (2017). PMID: 28264915 [pdf]
Thawani A, Tirumkudulu MS. Trajectory of a Model Bacterium. Journal of Fluid Mechanics (2017). [pdf]
Thawani A, Rajeev R, Sunoj RB. On the Mechanism of the Dehydroaromatization of Hexane to Benzene by an Iridium Pincer Catalyst. Chemistry (2013). PMID: 23364899 [pdf]
